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Guy A Rouleau Selected Research

Agenesis of Corpus Callosum

10/2019De Novo Pathogenic Variants in N-cadherin Cause a Syndromic Neurodevelopmental Disorder with Corpus Collosum, Axon, Cardiac, Ocular, and Genital Defects.
1/2013Potassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell volume decrease response with cell protrusion dynamics.

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Guy A Rouleau Research Topics

Disease

23Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2022 - 10/2004
22Bipolar Disorder (Manic Depressive Psychosis)
07/2022 - 04/2004
17Schizophrenia (Dementia Praecox)
11/2022 - 02/2003
16Parkinson Disease (Parkinson's Disease)
01/2021 - 09/2011
12Neurodegenerative Diseases (Neurodegenerative Disease)
01/2022 - 10/2003
12Oculopharyngeal Muscular Dystrophy
04/2019 - 08/2003
10Restless Legs Syndrome (Restless Legs)
01/2021 - 01/2004
10Intellectual Disability (Idiocy)
05/2017 - 12/2008
9Epilepsy (Aura)
05/2017 - 06/2002
9Autistic Disorder (Autism)
05/2016 - 01/2005
7Mood Disorders (Mood Disorder)
01/2021 - 12/2011
6Corpus callosum agenesis neuronopathy
10/2017 - 11/2002
6Hereditary Sensory and Motor Neuropathy (Dejerine Sottas Disease)
01/2016 - 09/2008
5Inflammation (Inflammations)
01/2020 - 03/2006
4Nervous System Diseases (Neurological Disorders)
01/2021 - 09/2012
4Dementia (Dementias)
01/2020 - 09/2012
4Autism Spectrum Disorder
05/2018 - 01/2015
4Pain (Aches)
01/2017 - 09/2007
4Idiopathic Generalized Epilepsy
01/2015 - 06/2002
4Migraine with Aura (Familial Hemiplegic Migraine)
10/2012 - 10/2010
4Juvenile Myoclonic Epilepsy
10/2005 - 06/2002
3Cognitive Dysfunction
11/2022 - 04/2020
3Psychotic Disorders (Schizoaffective Disorder)
11/2022 - 01/2020
3Genetic Risk Score
07/2022 - 01/2019
3Ataxia (Dyssynergia)
01/2020 - 09/2012
3Neurodevelopmental Disorders
10/2019 - 10/2011
3Hereditary Spastic Paraplegia
01/2019 - 06/2007
3Movement Disorders (Movement Disorder)
01/2018 - 11/2014
3Neoplasms (Cancer)
01/2017 - 01/2013
3Frontotemporal Dementia (Semantic Dementia)
06/2013 - 08/2004
3Angioedema
11/2011 - 10/2005
3Muscular Dystrophies (Muscular Dystrophy)
02/2010 - 10/2003
3Cardiovascular Diseases (Cardiovascular Disease)
04/2009 - 09/2005
3Generalized Epilepsy with Febrile Seizures Plus
10/2005 - 02/2003
2Synucleinopathies
01/2022 - 01/2017
2Mental Disorders (Mental Disorder)
01/2021 - 01/2016
2Cerebellar Ataxia (Dysmetria)
01/2020 - 06/2015
2Spinocerebellar Ataxias (Spinocerebellar Ataxia)
01/2020 - 06/2011
2Agenesis of Corpus Callosum
10/2019 - 01/2013
2Alzheimer Disease (Alzheimer's Disease)
02/2018 - 01/2018
2Essential Tremor (Essential Tremors)
01/2017 - 12/2016
2Neuralgia (Stump Neuralgia)
01/2017 - 03/2016
2REM Sleep Behavior Disorder
01/2017 - 11/2014
2Seizures (Absence Seizure)
11/2016 - 06/2002
2Congenital Pain Insensitivity
03/2016 - 11/2014
2Sleep Wake Disorders
11/2014 - 07/2011
2Late Onset Disorders
10/2014 - 04/2005
2Microcephaly
10/2013 - 01/2013
2Hereditary Sensory and Autonomic Neuropathies (HSAN)
01/2013 - 08/2011
2Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
11/2012 - 09/2011

Drug/Important Bio-Agent (IBA)

46Proteins (Proteins, Gene)FDA Link
01/2022 - 10/2003
20LithiumIBA
07/2022 - 04/2004
11polyalanineIBA
04/2019 - 10/2003
9DNA (Deoxyribonucleic Acid)IBA
11/2016 - 12/2003
8Nonsense Codon (Nonsense Mutation)IBA
11/2018 - 11/2010
7Biological ProductsIBA
01/2022 - 01/2007
7K Cl- CotransportersIBA
10/2017 - 11/2002
6Pharmaceutical PreparationsIBA
11/2022 - 04/2004
6Poly(A)-Binding Protein IIIBA
04/2019 - 04/2005
6UbiquitinIBA
01/2019 - 10/2003
6Potassium ChlorideFDA LinkGeneric
10/2017 - 09/2008
6Potassium Channels (Potassium Channel)IBA
10/2012 - 09/2005
5Biomarkers (Surrogate Marker)IBA
01/2022 - 08/2010
5Synapsins (Synapsin I)IBA
11/2016 - 01/2012
5EnzymesIBA
10/2016 - 09/2005
4Glucosylceramidase (Glucocerebrosidase)IBA
10/2016 - 09/2011
4Messenger RNA (mRNA)IBA
06/2016 - 09/2008
4Protein Isoforms (Isoforms)IBA
11/2015 - 09/2012
4Ion Channels (Ion Channel)IBA
08/2015 - 09/2005
4Immunoglobulin E (IgE)IBA
01/2015 - 06/2002
4Superoxide Dismutase-1IBA
10/2013 - 12/2007
3Dopamine (Intropin)FDA LinkGeneric
01/2021 - 03/2008
3CalciumIBA
01/2020 - 12/2008
3Antipsychotic Agents (Antipsychotics)IBA
01/2020 - 02/2003
3RNA (Ribonucleic Acid)IBA
04/2019 - 11/2015
3gamma-Aminobutyric Acid (GABA)IBA
06/2016 - 06/2002
3ChloridesIBA
01/2015 - 09/2005
3DNA-Binding Proteins (DNA Binding Protein)IBA
06/2013 - 09/2011
3IronIBA
01/2013 - 10/2007
3Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
11/2011 - 09/2005
33' Untranslated Regions (3' UTR)IBA
01/2011 - 12/2003
3Nuclear Proteins (Protein, Nuclear)IBA
02/2010 - 04/2005
3Sodium Channels (Sodium Channel)IBA
10/2005 - 02/2003
2Glutamic Acid (Glutamate)FDA Link
11/2022 - 01/2017
2SpectrinIBA
01/2020 - 07/2012
2polyglutamineIBA
01/2020 - 06/2011
2Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA
01/2020 - 01/2019
2SynucleinsIBA
01/2019 - 11/2014
2Ligases (Synthetase)IBA
01/2019 - 05/2015
2NucleotidesIBA
05/2018 - 01/2018
2Apolipoproteins E (ApoE)IBA
01/2018 - 01/2017
2Facilitative Glucose Transport Proteins (Glucose Transporter)IBA
05/2017 - 11/2016
2Forkhead Transcription Factors (Forkhead Box Proteins)IBA
01/2017 - 11/2010
2Chromogranin BIBA
11/2016 - 12/2009
2Aminobutyrates (Aminobutyric Acid)IBA
06/2016 - 03/2016
2DNA HelicasesIBA
05/2016 - 01/2013
2Arginine (L-Arginine)FDA Link
05/2015 - 11/2012
2Voltage-Gated Sodium ChannelsIBA
11/2014 - 02/2003
2Codon (Codons)IBA
10/2013 - 09/2007

Therapy/Procedure

5Therapeutics
12/2021 - 01/2017